Early surgery determines prognosis in patients with infective endocarditis: outcome in patients managed by an Endocarditis Team-a prospective cohort study.

ABSTRACT:

Background

Infective endocarditis (IE) in South Africa is associated with significant morbidity and mortality, despite occurring in younger patients with fewer co-morbidities. Possible contributors include the high rates of blood culture negative endocarditis, high rates of mechanical valve replacement and the lack of inter-disciplinary coordination during management.

Methods

The Tygerberg Endocarditis Cohort (TEC) study prospectively enrolled patients with IE between November 2019 and April 2021. All patients were managed by an Endocarditis Team with a set protocol for organism detection and a strategy of early surgery limiting the use of prosthetic material.

Results

Seventy-two consecutive patients with IE were included, with a causative organism identified in 86.1%

SUBMITTER: Pecoraro AJK 

PROVIDER: S-EPMC9412218 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature