Rapid and Sensitive Electrochemical Assay of Cefditoren with MWCNT/Chitosan NCs/Fe₂O₃ as a Nanosensor.

ABSTRACT: In this research, a glassy carbon electrode (GCE) modified by MWCNT/chitosan NCs/Fe₂O₃ was prepared for the determination of the cephalosporin antibiotic cefditoren (CFT) using adsorptive stripping differential pulse and cyclic voltammetry techniques. The effects of pH, the scan rate, the deposition potential, the accumulation time, and modification agents on the determination of CFT were analyzed. The results showed that the modified electrode significantly increased the oxidation peak current of CFT. Under optimized conditions, the MWCNT/chitosan NCs/Fe₂O₃/GCE nanosensor exhibited a linear response between 0.2 µM and 10 µM toward CFT. The limit of detection and quantification were determined to be 1.65 nM and 5.50 nM, respectively. Model drugs

SUBMITTER: Aydogdu N 

PROVIDER: S-EPMC9412661 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature