Association of rs1137101 with hypertension and type 2 diabetes mellitus of Mongolian and Han Chinese.

ABSTRACT:

Background

Hypertension (HTN) and type 2 diabetes mellitus (T2DM) are often coincident, and each condition is considered a risk factor for the other. Both occur frequently in the Inner Mongolia region of China. The reasons for differences in risk between Han and Mongolian ethnic groups are not known. The LEPR gene and its polymorphism, rs1137101 (Gln223Arg), are both considered risk factors for HTN and T2DM, but any role of rs1137101 in the occurrence of HTN + T2DM remains unclear for Mongolian and Han populations in the Inner Mongolia region.

Aim

To investigate the relationship between rs1137101 and the occurrence of HTN with T2DM in Mongolian and Han populations in Inner Mongolia.

Methods

A total of 2652 subjects of Han and Mongolian ethnic origins were enrol

SUBMITTER: Zhao KY 

PROVIDER: S-EPMC9412857 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature