Early intervention evidence for infants with or at risk for cerebral palsy: an overview of systematic reviews.

ABSTRACT:

Aim

To perform an overview of systematic reviews and more recent randomized controlled trials (RCTs) on early motor interventions in infants aged 0 to 3 years with or at risk of cerebral palsy to inform current clinical and research efforts and provide a benchmark to assess future interventions ideally initiated within the first 6 months.

Method

Standardized searches of the PubMed, Embase, Scopus, and Web of Science databases were conducted for systematic reviews (2009-2020) and RCTs (2015-2020).

Results

From 840 unique records, 31 full texts were reviewed, yielding three systematic reviews encompassing 46 studies, 16 with comparison groups, and six additional RCTs that met the criteria. Two enrichment- and activity-based approaches had medium effect sizes on motor de

SUBMITTER: Damiano DL 

PROVIDER: S-EPMC9413025 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature