Real-life impact of uncontrolled severe asthma on mortality and healthcare use in adolescents and adults: findings from the retrospective, observational RESONANCE study in France.

ABSTRACT:

Objective

To characterise uncontrolled severe asthma and compare the disease burden with the general and asthmatic populations.

Design

Retrospective observational study using a national sample of a French healthcare database (Echantillon Généraliste des Bénéficiaires (EGB)).

Setting

The EGB, an anonymised permanent sample of health insurance databases, representing 1/97th of the French population.

Participants

Patients (≥12 years) were selected in year 2014 and followed 2 years. A cohort of patients with uncontrolled severe asthma was defined using an algorithm based on peer-reviewed literature and Global Initiative for Asthma recommendations. Index date was the occurrence of the first marker of uncontrolled asthma. This cohort was matched with two control coho

SUBMITTER: Roche N 

PROVIDER: S-EPMC9413284 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature