An automated approach for predicting glioma grade and survival of LGG patients using CNN and radiomics.

ABSTRACT:

Objectives

To develop and validate an efficient and automatically computational approach for stratifying glioma grades and predicting survival of lower-grade glioma (LGG) patients using an integration of state-of-the-art convolutional neural network (CNN) and radiomics.

Method

This retrospective study reviewed 470 preoperative MR images of glioma from BraTs public dataset (n=269) and Jinling hospital (n=201). A fully automated pipeline incorporating tumor segmentation and grading was developed, which can avoid variability and subjectivity of manual segmentations. First, an integrated approach by fusing CNN features and radiomics features was employed to stratify glioma grades. Then, a deep-radiomics signature based on the integrated approach for predicting survival of LGG pa

SUBMITTER: Xu C 

PROVIDER: S-EPMC9413530 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature