Vasorelaxant Effect of Trachelospermi caulis Extract on Rat Mesenteric Resistance Arteries.

ABSTRACT:

Background

Trachelospermi caulis (T. caulis) has been used as a traditional herbal medicine in Asian countries. Although it is well known that T. caulis has beneficial effects, no sufficient research data are available on the cardiovascular effect of T. caulis. We investigated whether T. caulis extract has vascular effects in rat resistance arteries in this study.

Methods

To examine whether T. caulis extract affects vascular reactivity, we measured isometric tension of rat mesenteric resistance arteries using a multi-wire myograph system. T. caulis extract was administered after arteries were pre-contracted with high K⁺ (70 mM) or phenylephrine (5 µM). Vanillin, a single active component of T. caulis, was use

SUBMITTER: Haam CE 

PROVIDER: S-EPMC9413539 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature