Comparative Genomics of Escherichia coli Serotype O55:H7 Using Complete Closed Genomes.

ABSTRACT: Escherichia coli O55:H7 is a human foodborne pathogen and is recognized as the progenitor strain of E. coli O157:H7. While this strain is important from a food safety and genomic evolution standpoint, much of the genomic diversity of E. coli O55:H7 has been demonstrated using draft genomes. Here, we combine the four publicly available E. coli O55:H7 closed genomes with six newly sequenced closed genomes to provide context to this strain's genomic diversity. We found significant diversity within the 10 E. coli O55:H7 strains that belonged to three different sequence types. The prophage content was about 10% of the genome, with three prophages common to all strains and seven unique to one strain. Overall, there were 492 insertion sequences identified within

SUBMITTER: Weinroth MD 

PROVIDER: S-EPMC9413875 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature