Prognostic and clinicopathologic significance of circZFR in multiple human cancers.

ABSTRACT:

Background

Abnormally expressed in diverse cancers, circZFR has been correlated with clinical outcomes of cancer patients. Aim of this meta-analysis was to elucidate the prognostic role of circZFR in multiple human malignancies.

Methods

Literature retrieval was conducted by systematically searching on Pubmed, Web of Science, and the Cochrane Library up to December 2nd, 2021. Hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to evaluate the association between circZFR expression and overall survival (OS). The reliability of the pooled results was assessed through sensitivity analysis and the publication bias was measured by Begg's and Egger's test.

Results

A total of seventeen studies comprising 1098 Chinese patients were enrolled

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9413939 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature