Helicobacterpylori Infection-A Risk Factor for Irritable Bowel Syndrome? An Updated Systematic Review and Meta-Analysis.

ABSTRACT: Nowadays, the relationship between Helicobacter pylori infection (HPI) and irritable bowel syndrome (IBS) remains controversial.

Objective

The aim of this study is to investigate the relationship between HPI and IBS through a systematic review and meta-analysis based on the current evidence.

Methods

We performed a systematic literature search in electronic databases (PubMed, EMBASE, and the Cochrane library) by computer to identify all reports published before 8 August 2021. The odds ratio (OR) and confidence interval (CI) were calculated to evaluate the association between HPI and IBS. Subgroup analyses were conducted for further assessment and exploration of heterogeneity sources. In addition, we assessed publication bias through funnel plots, Egger's test, and Begg'

SUBMITTER: Wang Z 

PROVIDER: S-EPMC9413972 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature