Molecular characterization of colorectal cancer patients
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ABSTRACT:
SUBMITTER: Afanador CH
PROVIDER: S-EPMC9414253 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Publications
Molecular characterization of colorectal cancer patients
Afanador Carlos Humberto CH Palacio Katherine Andrea KA Isaza Luis Fernando LF Ahumada Enoc E Ocampo Carlos Mauricio CM Muñetón Carlos Mario CM
Biomedica : revista del Instituto Nacional de Salud 20220501 Sp. 1
Introduction: Colorectal cancer has a high incidence in the world population. Different molecular pathways, such as chromosomal instability, microsatellite instability, and epigenetics are involved in its development. Objective: To perform molecular characterization in 44 individuals with sporadic colorectal cancer. Materials and methods: We conducted mutation analyses of the APC, KRAS, TP53 y BRAF genes using Sanger sequencing techniques; microsatellite instability was determined by capillary e ...[more]
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