Bubble Formation in Pulsed Electric Field Technology May Pose Limitations.

ABSTRACT: Currently, increasing amounts of pulsed electric fields (PEF) are employed to improve a person's life quality. This technology is based on the application of the shortest high voltage electrical pulse, which generates an increment over the cell membrane permeability. When applying these pulses, an unwanted effect is electrolysis, which could alter the treatment. This work focused on the study of the local variations of the electric field and current density around the bubbles formed by the electrolysis of water by PEF technology and how these variations alter the electroporation protocol. The assays, in the present work, were carried out at 2 KV/cm, 1.2 KV/cm and 0.6 KV/cm in water, adjusting the conductivity with NaCl at 2365 μs/cm with a single pulse of 800 μs. The measurements of the bu

SUBMITTER: Rodriguez Osuna IA 

PROVIDER: S-EPMC9414362 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature