Early hyperoxia and 28-day mortality in patients on venoarterial ECMO support for refractory cardiogenic shock: a bicenter retrospective propensity score-weighted analysis.

ABSTRACT:

Background

The mortality rate for a patient with a refractory cardiogenic shock on venoarterial (VA) extracorporeal membrane oxygenation (ECMO) remains high, and hyperoxia might worsen this prognosis. The objective of the present study was to evaluate the association between hyperoxia and 28-day mortality in this setting.

Methods

We conducted a retrospective bicenter study in two French academic centers. The study population comprised adult patients admitted for refractory cardiogenic shock. The following arterial partial pressure of oxygen (PaO₂) variables were recorded for 48 h following admission: the absolute peak PaO₂ (the single highest value measured during the 48 h), the mean daily peak PaO₂ (the mean of each day's peak values), the o

SUBMITTER: Moussa MD 

PROVIDER: S-EPMC9414410 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature