Detoxification Response of Pseudomonas fluorescens MFAF76a to Gaseous Pollutants NO₂ and NO.

ABSTRACT: Bacteria are often exposed to nitrosative stress from their environment, from atmospheric pollution or from the defense mechanisms of other organisms. Reactive nitrogen species (RNS), which mediate nitrosative stress, are notably involved in the mammalian immune response through the production of nitric oxide (NO) by the inducible NO synthase iNOS. RNS are highly reactive and can alter various biomolecules such as lipids, proteins and DNA, making them toxic for biological organisms. Resistance to RNS is therefore important for the survival of bacteria in various environments, and notably to successfully infect their host. The fuel combustion processes used in industries and transports are responsible for the emission of important quantities of two major RNS, NO and the more toxic nitrogen

SUBMITTER: Chautrand T 

PROVIDER: S-EPMC9414441 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature