Isolation and Characterization of the Lytic Pseudoxanthomonas kaohsiungensi Phage PW916.

ABSTRACT: The emergence of multidrug-resistant bacterial pathogens poses a serious global health threat. While patient infections by the opportunistic human pathogen Pseudoxanthomonas spp. have been increasingly reported worldwide, no phage associated with this bacterial genus has yet been isolated and reported. In this study, we isolated and characterized the novel phage PW916 to subsequently be used to lyse the multidrug-resistant Pseudoxanthomonas kaohsiungensi which was isolated from soil samples obtained from Chongqing, China. We studied the morphological features, thermal stability, pH stability, optimal multiplicity of infection, and genomic sequence of phage PW916. Transmission electron microscopy revealed the morphology of PW916 and indicated it to belong to the Siphovirida

SUBMITTER: Wen C 

PROVIDER: S-EPMC9414467 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature