Accelerometer-Based Sedentary Time, Physical Activity, and Serum Metabolome in Young Men.

ABSTRACT: Physical activity (PA) has been shown to associate with many health benefits but studies with metabolome-wide associations with PA are still lacking. Metabolome studies may deepen the mechanistic understanding of PA on the metabolic pathways related to health outcomes. The aim of the present study was to study the association of accelerometer based sedentary time (SB) and PA with metabolome measures. SB and PA were measured by a hip-worn accelerometer in 314 young adult men (age: mean 28, standard deviation 7 years). Metabolome was analyzed from fasting serum samples consisting of 66 metabolome measures (nuclear magnetic resonance-based metabolomics). The associations were analyzed using a single and compositional approach with regression analysis. The compositional analysis revealed that

SUBMITTER: Vaara JP 

PROVIDER: S-EPMC9414649 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature