The Gene Expression Profile Differs in Growth Phases of the Bifidobacterium Longum Culture.

ABSTRACT: To date, transcriptomics have been widely and successfully employed to study gene expression in different cell growth phases of bacteria. Since bifidobacteria represent a major component of the gut microbiota of a healthy human that is associated with numerous health benefits for the host, it is important to study them using transcriptomics. In this study, we applied the RNA-Seq technique to study global gene expression of B. longum at different growth phases in order to better understand the response of bifidobacterial cells to the specific conditions of the human gut. We have shown that in the lag phase, ABC transporters, whose function may be linked to active substrate utilization, are increasingly expressed due to preparation for cell division. In the exponential phase, the func

SUBMITTER: Veselovsky VA 

PROVIDER: S-EPMC9415070 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature