Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics.

ABSTRACT: Globally, cancer is amongst the most deadly diseases due to the low efficiency of the conventional and obsolete chemotherapeutic methodologies and their many downsides. The poor aqueous solubility of most anticancer medications and their low biocompatibility make them ineligible candidates for the design of delivery systems. A significant drawback associated with chemotherapy is that there are no advanced solutions to multidrug resistance, which poses a major obstacle in cancer management. Since RNA interference (RNAi) can repress the expression of genes, it is viewed as a novel tool for advanced drug delivery. this is being explored as a promising drug targeting strategy for the treatment of multiple diseases, including cancer. However, there are many obstructions that hinder the clinical

SUBMITTER: Zare M 

PROVIDER: S-EPMC9416290 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature