Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes.

ABSTRACT: An efficient method for the selective preparation of trifluoromethyl-substituted azepin-2-carboxylates and their phosphorous analogues has been developed via Cu(I)-catalyzed tandem amination/cyclization reaction of functionalized allenynes with primary and secondary amines.

SUBMITTER: Philippova AN 

PROVIDER: S-EPMC9416787 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature