Hydrophobic soot nanoparticles as a non-cytotoxic motility activator of human spermatozoa.

ABSTRACT: Sperm cryopreservation is vital in combating the human infertility, but regrettably, the toxicity of cryoprotectants and the occurrence of intracellular icing, osmotic shocks or shrinkage of the cells below a given threshold volume greatly affects the success rate of this technique. Using the virtue of nanotechnologies and depositing water-repellent soot nanoparticles on the inner walls of cryovials may outline new directions in the development of cryobiology, but doubts related to the soot's venomosity question its practical implementability. The scientific content of this article eliminates the existing apprehensions by analyzing the cytotoxicity of three types of rapeseed oil soot, differing in morphology, surface chemistry and zeta potential, towards human spermatozoa. Upon intermitten

SUBMITTER: Esmeryan KD 

PROVIDER: S-EPMC9417005 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature