Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations.

ABSTRACT: The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.

SUBMITTER: Hobson JJ 

PROVIDER: S-EPMC9417103 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature