Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations.
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ABSTRACT:
SUBMITTER: Hobson JJ
PROVIDER: S-EPMC9417103 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
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Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations.
Hobson James J JJ Curley Paul P Savage Alison C AC Al-Khouja Amer A Siccardi Marco M Flexner Charles C Meyers Caren Freel CF Owen Andrew A Rannard Steve P SP
Nanoscale advances 20191012 11
The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media. ...[more]
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