One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents.

ABSTRACT: A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au⁰ core, vanadium and alendronate) acting synergistically.

SUBMITTER: Tomane S 

PROVIDER: S-EPMC9417735 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature