Analysis of nocturnal desaturation waveforms using algorithms in patients with idiopathic pulmonary fibrosis.

ABSTRACT:

Purpose

Sleep-disordered breathing is recognized as a comorbidity in patients with idiopathic pulmonary fibrosis (IPF). Among them, nocturnal hypoxemia has been reported to be associated with poor prognosis and disease progression. We developed a diagnostic algorithm to classify nocturnal desaturation from percutaneous oxygen saturation (SpO₂) waveform patterns: sustained pattern, periodic pattern, and intermittent pattern. We then investigated the prevalence of nocturnal desaturation and the association between the waveform patterns of nocturnal desaturation and clinical findings of patients with IPF.

Methods

We prospectively enrolled patients with IPF from seven general hospitals between April 2017 and March 2020 and measured nocturnal SpO₂ and nasal

SUBMITTER: Yasuda Y 

PROVIDER: S-EPMC9418279 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature