Nanoprobes to investigate nonspecific interactions in lipid bilayers: from defect-mediated adhesion to membrane disruption.

ABSTRACT: When a lipid membrane approaches a material/nanomaterial, nonspecific adhesion may occur. The interactions responsible for nonspecific adhesion can either preserve the membrane integrity or lead to its disruption. Despite the importance of the phenomenon, there is still a lack of clear understanding of how and why nonspecific adhesion may originate different resulting scenarios and how these interaction scenarios can be investigated. This work aims at bridging this gap by investigating the role of the interplay between cationic electrostatic and hydrophobic interactions in modulating the membrane stability during nonspecific adhesion phenomena. Here, the stability of the membrane has been studied employing anisotropic nanoprobes in zwitterionic lipid membranes with the support of coarse-gr

SUBMITTER: Razza N 

PROVIDER: S-EPMC9418973 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature