A gold nanoparticle-intercalated mesoporous silica-based nanozyme for the selective colorimetric detection of dopamine.

ABSTRACT: Highly dispersed aggregation-free gold nanoparticles intercalated into the walls of mesoporous silica (AuMS) were synthesized using thioether-functionalized silica as a nanozyme, which exhibited an excellent peroxidase mimic activity. The AuMS material was characterized via XRD, N₂ adsorption-desorption, FESEM, SEM-EDS particle mapping, TEM, and XPS. The peroxidase-like activity of the AuMS material was studied thoroughly, and the effect of pH and temperature was evaluated. The reproducibility of the peroxidase mimic activity and long-term stability of the AuMS catalyst were also studied. Furthermore, the AuMS catalyst was successfully utilized for the detection and quantification of dopamine, an important neurotransmitter, colorimetrically with a linear range of 10-80 μM

SUBMITTER: Ray S 

PROVIDER: S-EPMC9418996 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature