Graphene BioFET sensors for SARS-CoV-2 detection: a multiscale simulation approach.

ABSTRACT: Biological Field-Effect Transistors (BioFETs) have already demonstrated enormous potential for detecting minute amounts of ions and molecules. The use of two-dimensional (2D) materials has been shown to boost their performance and to enable the design of new applications. This combination deserves special interest in the current pandemic caused by the SARS-CoV-2 virus which demands fast, reliable and cheap detection methods. However, in spite of the experimental advances, there is a lack of a comprehensive and in-depth computational approach to capture the mechanisms underlying the sensor behaviour. Here, we present a multiscale platform that combines detailed atomic models of the molecules with mesoscopic device-level simulations. The fine-level description exploited in this approach acco

SUBMITTER: Toral-Lopez A 

PROVIDER: S-EPMC9418999 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature