White matter abnormalities characterize the acute stage of sports-related mild traumatic brain injury.

ABSTRACT: Sports-related concussion, a form of mild traumatic brain injury, is characterized by transient disturbances of brain function. There is increasing evidence that functional brain changes may be driven by subtle abnormalities in white matter microstructure, and diffusion MRI has been instrumental in demonstrating these white matter abnormalities in vivo. However, the reported location and direction of the observed white matter changes in mild traumatic brain injury are variable, likely attributable to the inherent limitations of the white matter models used. This cross-sectional study applies an advanced and robust technique known as fixel-based analysis to investigate fibre tract-specific abnormalities in professional Australian Football League players with a recent mild traumatic b

SUBMITTER: Mito R 

PROVIDER: S-EPMC9419063 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature