Sieving nanometer enantiomers using bound states in the continuum from the metasurface.

ABSTRACT: Enantioseparation of chiral molecules is an important aspect of life sciences, chemical syntheses, and physics. Yet, the prevailing chemical techniques are not effective. Recently, a few types of plasmonic apertures have been theoretically proposed to distinguish between chiral molecules that vary based on their handedness under circularly polarized illumination. Both analytic calculations and numerical simulation demonstrated that enantioselective optical sieving could be obtained at the nanoscale using a large chiral optical force based on plasmonic resonance enhanced near-field chiral gradients in the aperture. Nevertheless, scaling this scheme to chiral entities of a few nanometer size (i.e., proteins and DNA) faces formidable challenges owing to the fabrication limit of a deepl

SUBMITTER: Mao L 

PROVIDER: S-EPMC9419565 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature