Characterizing and Engineering Biomimetic Materials for Viscoelastic Mechanotransduction Studies.

ABSTRACT: The mechanical behavior of soft tissue extracellular matrix is time dependent. Moreover, it evolves over time due to physiological processes as well as aging and disease. Measuring and quantifying the time-dependent mechanical behavior of soft tissues and materials pose a challenge, not only because of their labile and hydrated nature but also because of the lack of a common definition of terms and understanding of models for characterizing viscoelasticity. Here, we review the most important measurement techniques and models used to determine the viscoelastic properties of soft hydrated materials-or hydrogels-underlining the difference between viscoelastic behavior and the properties and descriptors used to quantify viscoelasticity. We then discuss the principal factors, which determine ti

SUBMITTER: Cacopardo L 

PROVIDER: S-EPMC9419958 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature