Two-dimensional silicene photodynamic tumor-targeting nanomedicine.

ABSTRACT: Since the innovative development of photosensitizers (PSs) is pivotal prerequisite for the successful clinical translation of photodynamic therapy (PDT), the unresolved challenges of classical PSs such as photobleaching, poor bioavailability, lack of tumor selectivity encourage the exploitation of new-generation PSs. In this work, we develop silicene nanosheets with unparalleled physiochemical nature and intriguing biocompatibility as the distinct two-dimensional (2D) nanoscale photosensitizer based on the mechanism of wet-chemical synthetic approach to achieve effective PDT-based tumor nanotherapy. The generation capacities of singlet oxygen (¹O₂) in different atmospheres have been systematically explored in depth. Furthermore, the conjunction of c (RGDyC) onto 2D si

SUBMITTER: Duan H 

PROVIDER: S-EPMC9420369 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature