County-level Differences in Liver-related Mortality, Waitlisting, and Liver Transplantation in the United States.

ABSTRACT:

Background

Much of our understanding regarding geographic issues in transplantation is based on statistical techniques that do not formally account for geography and is based on obsolete boundaries such as donation service area.

Methods

We applied spatial epidemiological techniques to analyze liver-related mortality and access to liver transplant services at the county level using data from the Centers for Disease Control and Prevention and Scientific Registry of Transplant Recipients from 2010 to 2018.

Results

There was a significant negative spatial correlation between transplant rates and liver-related mortality at the county level (Moran's I, -0.319; P  = 0.001). Significant clusters were identified with high transplant rates and low liver-related mortality. Count

SUBMITTER: Cannon RM 

PROVIDER: S-EPMC9420757 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature