Measurement of magnetostimulation thresholds in the porcine heart.

ABSTRACT:

Purpose

Powerful MRI gradient systems can surpass the International Electrotechnical Commission (IEC) 60601-2-33 limit for cardiac stimulation (CS), which was determined by simple electromagnetic simulations and electrode stimulation experiments. Only a few canine studies measured magnetically induced CS thresholds in vivo and extrapolating them to human safety limits can be challenging.

Methods

We measured cardiac magnetostimulation thresholds in 10 healthy, anesthetized pigs using capacitors discharged into a flat spiral coil to produce damped sinusoidal waveforms with effective stimulus duration t_s,eff  = 0.45 ms. Electrocardiography (ECG), blood pressure, and peripheral oximetry signals were recorded to determine threshold coil currents yielding cardiac captur

SUBMITTER: Klein V 

PROVIDER: S-EPMC9420805 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature