Urinary nitrate and sodium in a high-risk area for upper gastrointestinal cancers: Golestan Cohort Study^☆.

ABSTRACT:

Background

The epidemiological evidence regarding the carcinogenicity of nitrate and sodium in drinking water is limited, partly because measuring the exposure at the individual level is complex. Most studies have used nitrate in water supplies as a proxy for individual exposure, but dietary intakes and other factors may contribute to the exposure. The present study investigates the factors associated with urinary nitrate and sodium in a high-risk area for esophageal and gastric cancers.

Methods

For this cross-sectional study, we used data and samples collected in 2004-2008 during the enrollment phase of the Golestan Cohort Study from a random sample of 349 participants (300 individuals from 24 rural villages and 49 from the city of Gonbad), stratified by average water nitra

SUBMITTER: Etemadi A 

PROVIDER: S-EPMC9420831 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature