Hippocampal maintenance after a 12-month physical activity intervention in older adults: The REACT MRI study.

ABSTRACT:

Background

Physical activity interventions have had varying results on modifying hippocampal volume.

Methods

The Retirement in Action (REACT) study conducted a randomised-controlled trial of a 12-month physical activity and behaviour maintenance intervention in older adults at risk of mobility impairments. The physical activity sessions were delivered twice weekly for the first twelve weeks, and then reduced to once weekly, to groups of 15 participants. Activities included cardiovascular, strength, balance and flexibility exercises. A sub-sample of participants in the physical activity (N = 54) and control arms (N = 48) underwent a 3 T MRI brain scan and cognitive assessments at baseline, 6- and 12-months (mean age = 76.6 years, 6.8 SD). It was hypothesised that the interven

SUBMITTER: Demnitz N 

PROVIDER: S-EPMC9421470 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature