Simplified Edinburgh and modified Boston criteria in relation to amyloid PET for lobar intracerebral hemorrhage.

ABSTRACT:

Background

Histopathological evidence of cerebral vascular amyloid β accumulation is the gold standard to diagnose cerebral amyloid angiopathy (CAA). Neuroimaging findings obtained with CT and MRI can suggest the presence of CAA when histopathology is lacking. We explored the role of amyloid PET in patients with lobar intracerebral hemorrhage (ICH) as this may provide molecular evidence for CAA as well.

Methods

In this retrospective, monocenter analysis, we included consecutive patients with non-traumatic lobar ICH who had undergone amyloid PET. We categorized patients according to amyloid PET status and compared demographics and neuroimaging findings. We calculated sensitivity and specificity of the simplified Edinburgh criteria and amyloid PET with probable modified Boston

SUBMITTER: Michiels L 

PROVIDER: S-EPMC9421490 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature