Altered brain network topology in children with auditory processing disorder: A resting-state multi-echo fMRI study.

ABSTRACT: Children with auditory processing disorder (APD) experience hearing difficulties, particularly in the presence of competing sounds, despite having normal audiograms. There is considerable debate on whether APD symptoms originate from bottom-up (e.g., auditory sensory processing) and/or top-down processing (e.g., cognitive, language, memory). A related issue is that little is known about whether functional brain network topology is altered in APD. Therefore, we used resting-state functional magnetic resonance imaging data to investigate the functional brain network organization of 57 children from 8 to 14 years old, diagnosed with APD (n = 28) and without hearing difficulties (healthy control, HC; n = 29). We applied complex network analysis using graph theory to assess the whole-brain inte

SUBMITTER: Alvand A 

PROVIDER: S-EPMC9421544 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature