Coupled plasma filtration adsorption for the treatment of sepsis or septic shock: a systematic review and meta-analysis.

ABSTRACT:

Background

The effect of coupled plasma filtration adsorption (CPFA) for the treatment of sepsis or septic shock is controversial. A systematic review and meta-analysis was performed to evaluate the impact of CPFA on all-cause mortality in patients with sepsis or septic shock.

Methods

We searched the PubMed, Cochrane, and Embase databases for randomized controlled trials (RCTs) and cohort studies from inception to the 1st of May 2022. We included studies involving patients (˃ 14 years) with sepsis or septic shock. All authors reported our primary outcome of all-cause mortality (hospital mortality, 28-day mortality or 30-day mortality). Results were expressed as odds ratio (OR) with accompanying 95% confidence interval (CI).

Results

Six studies including 537 patients w

SUBMITTER: Li Y 

PROVIDER: S-EPMC9422100 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature