Proteome-wide analysis of lysine 2-hydroxyisobutyrylation in Frankliniella occidentalis.

ABSTRACT:

Background

Lysine 2-hydroxyisobutyrylation (Khib) is a novel and conserved post-translational modification (PTM). Frankliniella occidentalis are economically important agricultural pests globally and also notorious for vectoring destructive plant viruses. To better study the disease transmission mechanism of F. occidentalis, it is necessary to conduct in-depth analysis of it. So far, no Khib modification of insects has been reported.

Results

In this study, a proteome-wide analysis of Khib modifications in F. occidentalis was analyzed for the first time through the combination of high performance liquid chromatography fractionation technology and 2-hydroxyisobutyrylated peptide enrichment and other advanced technologies, 4093 Khib sites were identified on 1125 modified protei

SUBMITTER: Ding C 

PROVIDER: S-EPMC9422105 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature