SVR achievement in triple therapy treated hepatitis C induced cirrhosis: A dual center retrospective cohort study.

ABSTRACT:

Background and objective

Multiple prospective and retrospective cohort studies from the West have demonstrated the conflicting results about the efficacy of direct-acting antivirals (DAAs) by sustained virologic response (SVR) achievement rate in hepatitis C virus (HCV) infected patients. But there is limited to no data about the effectiveness of triple therapy ribavirin-sofosbuvir-daclatasvir in cirrhotic hepatitis C infected patients from Pakistan.

Methods

We conducted a retrospective cohort study by retrieving records of 359 hepatitis C infected patients treated with triple therapy from two tertiary care hospitals in Pakistan [Cirrhotic = 187 (53%); non-cirrhotic = 172 (47%)] from February 18, 2018, to June 29, 2019. We lost the follow-up of 158 (44.1%) patients due to de

SUBMITTER: Sheikh NT 

PROVIDER: S-EPMC9422198 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature