Anti-tuberculosis drug-induced liver injury in patient with hepatitis B and cirrhosis: A case report.

ABSTRACT:

Background

Pulmonary tuberculosis patients infected with hepatitis B are at high risk for drug-induced liver injury.

Case presentation

A 42-year-old Indonesian female complained of sclera icterus, tea-colored urine, vomiting, dyspnea, and swollen stomach and legs. The patient experienced this condition after taking anti-tuberculosis drugs for five days. Her medical history showed hepatitis B and cirrhosis. Follow-up examination included chest X-ray and GeneXpert supported a diagnosis of pulmonary tuberculosis. However, abdominal ultrasonography indicated ascites and cirrhosis. We diagnosed the patient with anti-tuberculosis DILI, cirrhosis Child-Pugh C (score 12) related to hepatitis B, and pulmonary tuberculosis. We decided to stop the anti-tuberculosis drug. We treated the

SUBMITTER: Aminy RZ 

PROVIDER: S-EPMC9422211 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature