Smartphone-Based Photoelectrochemical Immunoassay with Co₉S₈@ZnIn₂S₄ for Point-of-Care Diagnosis of Breast Cancer Biomarker.

ABSTRACT: Photoelectrochemical immunoassays incorporating specific antigen-antibody recognition reactions with the photon-electron conversion capabilities of photocatalysts have been developed for biomarker detection, but most involve bulky and expensive equipment and are unsuitable for point-of-care testing. Herein, a portable smartphone-based photoelectrochemical immunoassay was innovatively designed for the on-site detection of breast cancer biomarkers (human epidermal growth factor receptor 2; HER2). The system consists of a split-type immunoassay mode, disposable screen-printed electrode covered with hierarchical Co₉S₈@ZnIn₂S₄ heterostructures, an integrated circuit board, and a Bluetooth smartphone equipped with a specially designed app. Using alkali

SUBMITTER: Zeng R 

PROVIDER: S-EPMC9422330 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature