The risk of nonsyndromic cleft lip with or without cleft palate and Vax1 rs7078160 polymorphisms in southern Han Chinese.

ABSTRACT:

Introduction

Non-syndromic cleft lip with or without cleft palate is a common worldwide birth defect due to a combination of environmental and genetic factors. Genome-wide association studies reported the rs7078160 of Vax1 is closely related to non-syndromic cleft lip with or without cleft palate in European populations. The following studies showed the same results in Mongolian, Japanese, Filipino, Vietnamese populations etc. However, conflicting research had been reported in Chinese population, OBJECTIVE: The aim of this study was to investigate the association between the rs7078160 polymorphism and non-syndromic cleft lip with or without cleft palate in Southern Chinese patients.

Methods

In this study, we investigated the polymorphism distribution of rs7078160 in 100 comp

SUBMITTER: Wang Q 

PROVIDER: S-EPMC9422622 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature