Cohort profile: population-based cohorts of patients with colorectal cancer and of their relatives in Geneva, Switzerland.

ABSTRACT:

Purpose

Colorectal cancer (CRC) is the third leading cause of cancer death worldwide. Variability between patients in prognosis and treatment response is partially explained by traditional clinicopathological factors. We established a large population-based cohort of patients with CRC and their first-degree and second-degree relatives registered in the Canton of Geneva, to evaluate the role of family history and tumour biomarkers on patient outcomes.

Participants

The cohort includes all patients with CRC diagnosed between 1985 and 2013. Detailed information on patient and tumour characteristics, treatment and outcomes were extracted from the Geneva Cancer Registry database, completed by medical records review and linkage with administrative and oncogenetics databases. Next-g

SUBMITTER: Benhamou S 

PROVIDER: S-EPMC9422819 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature