Slowly absorbable mesh versus standard care in the management of contaminated midline incisional hernia (COMpACT-BIO): a multicentre randomised controlled phase III trial including a health economic evaluation.

ABSTRACT:

Introduction

Incisional hernia (IH) is the most frequent mid-term and long-term complication after midline laparotomy. The current standard treatment includes repair using a mesh. In a contaminated field, the use of a non-absorbable mesh increases the risk of surgical site infection and the costs. Slowly absorbable meshes are safe in contaminated fields, but no data have been reported regarding their long-term recurrence rate. COMpACT-BIO is a multicentre prospective randomised controlled phase III trial designed to compare the 3-year recurrence rate in patients undergoing contaminated IH repair with either a slowly absorbable mesh or standard care.

Methods

In patients undergoing midline IH repair in a contaminated surgical field (grade III of the modified Ventral Hernia Wor

SUBMITTER: Passot G 

PROVIDER: S-EPMC9422840 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature