Intraoperative Remifentanil Infusion and Postoperative Pain Outcomes After Cardiac Surgery-Results from Secondary Analysis of a Randomized, Open-Label Clinical Trial.

ABSTRACT:

Design

Report of secondary pain outcomes from a prospective, randomized, open-label clinical trial that compared remifentanil and fentanyl on perioperative hyperglycemic response in cardiac surgery.

Setting

Single institution, tertiary university hospital.

Participants

The study comprised 116 adult elective cardiac surgical patients.

Interventions

Participants were randomly assigned to receive either intermittent fentanyl boluses (F) or continuous remifentanil infusion (R) intraoperatively.

Measurements and main results

Postoperative pain was evaluated with pain scores every 6 hours for 48 hours. Pain threshold to mechanical stimuli was measured around the sternotomy incision at 48 and 96 hours. The development of chronic pain was assessed using the nume

SUBMITTER: Subramaniam K 

PROVIDER: S-EPMC9423078 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature