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Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus.

ABSTRACT: We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.

SUBMITTER: Quizon K 

PROVIDER: S-EPMC9423932 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus.

Quizon Kaye K   Holloway Kimberly K   Iranpour Mahmood M   Warner Bryce M BM   Deschambault Yvon Y   Soule Geoff G   Tierney Kevin K   Kobasa Darwyn D   Sloan Angela A   Safronetz David D  

Emerging infectious diseases 20220901 9

We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV. ...[more]

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