Molecular detection of SARS-COV-2 in exhaled breath at the point-of-need.

ABSTRACT: The SARS-CoV-2 pandemic has highlighted the need for improved technologies to help control the spread of contagious pathogens. While rapid point-of-need testing plays a key role in strategies to rapidly identify and isolate infectious patients, current test approaches have significant shortcomings related to assay limitations and sample type. Direct quantification of viral shedding in exhaled particles may offer a better rapid testing approach, since SARS-CoV-2 is believed to spread mainly by aerosols. It assesses contagiousness directly, the sample is easy and comfortable to obtain, sampling can be standardized, and the limited sample volume lends itself to a fast and sensitive analysis. In view of these benefits, we developed and tested an approach where exhaled particles are efficiently

SUBMITTER: Stakenborg T 

PROVIDER: S-EPMC9424122 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature