Associations of self-reported occupational exposures and settings to ALS: a case-control study.

ABSTRACT:

Background

Environmental exposures contribute to the pathogenesis of amyotrophic lateral sclerosis (ALS), a fatal and progressive neurological disease. Identification of these exposures is important for targeted screening and risk factor modification.

Objective

To identify occupational exposures that are associated with a higher risk of ALS using both survey and standard occupational classification (SOC) coding procedures, and to highlight how exposure surveys can complement SOC coding.

Methods

ALS participants and neurologically healthy controls recruited in Michigan completed a detailed exposure assessment on their four most recent and longest held occupations. Exposure scores were generated from the exposure survey, and occupations were assigned to SOC codes by exp

SUBMITTER: Goutman SA 

PROVIDER: S-EPMC9424174 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature