Stable Sparse Classifiers predict cognitive impairment from gait patterns.

ABSTRACT:

Background

Although gait patterns disturbances are known to be related to cognitive decline, there is no consensus on the possibility of predicting one from the other. It is necessary to find the optimal gait features, experimental protocols, and computational algorithms to achieve this purpose.

Purposes

To assess the efficacy of the Stable Sparse Classifiers procedure (SSC) for discriminating young and healthy older adults (YA vs. HE), as well as healthy and cognitively impaired elderly groups (HE vs. MCI-E) from their gait patterns. To identify the walking tasks or combinations of tasks and specific spatio-temporal gait features (STGF) that allow the best prediction with SSC.

Methods

A sample of 125 participants (40 young- and 85 older-adults) was studied. They unde

SUBMITTER: Aznielle-Rodriguez T 

PROVIDER: S-EPMC9425080 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature