Hepatitis B virus infection among institutionalized mentally ill patients in Brazil.

ABSTRACT:

Objectives

The main objective was to evaluate HBV infection and occult HBV infection (OBI) cases in mentally ill patients based on serological and molecular profiles.

Material and methods

Serum samples of 333 long-stay mentally ill patients were tested for the prevalence of HBV markers by serological (ELISA) and molecular (PCR) assays. The PCR products were sequenced to determine viral genotypes.

Results

It was observed a global prevalence of 12.9% (43/333) for HBV infection markers, considering HBsAg and/or anti-HBc positivity. Fourteen samples tested positive for anti-HBs alone. All samples positive (n=57) for any HBV serological markers were tested for HBV-DNA and six were positive: HBsAg/anti-HBc (n=1), anti-HBc/anti-HBs (n=1), anti-HBs alone (n=1), and anti-HBc a

SUBMITTER: Moraes TC 

PROVIDER: S-EPMC9425346 | biostudies-literature | 2015 Nov-Dec

REPOSITORIES: biostudies-literature